The incident occurred shortly after 6.30pm on Monday in Farranshock Estate, Mullingar.
He was treated at the scene before being taken by ambulance to Mullingar Hospital, where he was pronounced deceased.
The Coroner has been notified, and a post-mortem examination will be arranged.
The scene is currently preserved for examination by Garda Forensic Collision Investigators.
Gardaí are appealing to anyone who may have witnessed the collision to come forward.
Meanwhile, in a separate collision in Sligo, a nine-year-old boy, a three-year-old girl and two women were seriously injured in a crash.
The incident was followed by a separate collision in Co Limerick in which a motorcyclist, aged in his 20s, died.
Today’s News in 90 Seconds – April 22nd
While a fourth collision took place in Co Kilkenny on Sunday in which another man, aged in his 30s, suffered serious injuries following a collision involving a car and a motorcycle.
Gardaí were called to the scene of the collision in Co Sligo on Monday between two cars on the N59 in Ballysadare in Sligo around 2.30pm.
Two women, one aged in her 40s and the other in her 20s, and the two children were brought to Sligo University Hospital with serious injuries.
The driver and sole occupant of the second car, a woman in her 50s, was brought to the hospital for assessment.
Local diversions are in place while gardaí carry out an examination of the scene.
In Co Limerick a man, aged in his 20s, died following a collision between a motorcycle and a car.
The incident took place in Ardagh village at the intersection of the R521 and R523. The motorcyclist was pronounced dead at the scene. His body was removed to University Hospital Limerick where a postmortem will take place.
The male driver of the car was brought to University Hospital Kerry for treatment for non-life-threatening injuries.
The intersection where the incident occurred remained closed overnight ahead of a technical examination to be carried out by gardaí on Tuesday morning.
Meanwhile, the incident in Kilkenny took place around 12.40pm on Sunday afternoon on the R448 at Knockwilliam.
The motorcyclist involved in the collision, a man in his 30s, was taken to the Mater Misericordiae University Hospital, where he remains in serious condition.
No injuries were reported as a result of the collision.
Gardaí are appealing for any witnesses to this incident to come forward.
Any road users who may have camera footage (including dash-cam) and were travelling in the area at the time are asked to make this footage available to investigating gardaí.
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